Structure of PDB 6ip6 Chain 2f

Receptor sequence
>6ip62f (length=50) Species: 9606 (Homo sapiens) [Search protein sequence]
SSHKTFRIKRFLAKKQKQNRPIPQWIRMKTGNKIRYNSKRRHWRRTKLGL
3D structure
PDB6ip6 HCV IRES Captures an Actively Translating 80S Ribosome.
Chain2f
Resolution4.5 Å
3D
structure
[Spin on]
[Spin off]
[Reset orientation]

[High quality]
[Low quality]

[White background]
[Black background]

[Download]
[Download structure with residue number starting from 1]
Enzymatic activity
Enzyme Commision number ?
Interaction with ligand
Site
#
Ligand Ligand
chain
Binding residues on receptor
(original residue number in PDB)
Binding residues on receptor
(residue number reindexed from 1)
Binding affinity
BS01 rna 2f S2 S3 H4 K5 K10 L13 Q17 K34 I35 R36 N38 S39 R41 R42 H43 W44 R45 T47 K48 L49 S1 S2 H3 K4 K9 L12 Q16 K33 I34 R35 N37 S38 R40 R41 H42 W43 R44 T46 K47 L48
BS02 rna 2f F7 R8 R11 K15 K18 Q19 I23 P24 W26 M29 T31 K40 F6 R7 R10 K14 K17 Q18 I22 P23 W25 M28 T30 K39
Gene Ontology
Molecular Function
GO:0003723 RNA binding
GO:0003735 structural constituent of ribosome
Biological Process
GO:0002181 cytoplasmic translation
GO:0002227 innate immune response in mucosa
GO:0006412 translation
GO:0019731 antibacterial humoral response
GO:0050830 defense response to Gram-positive bacterium
GO:0061844 antimicrobial humoral immune response mediated by antimicrobial peptide
Cellular Component
GO:0005615 extracellular space
GO:0005737 cytoplasm
GO:0005829 cytosol
GO:0005840 ribosome
GO:0022625 cytosolic large ribosomal subunit
GO:0022626 cytosolic ribosome
GO:1990904 ribonucleoprotein complex

View graph for
Molecular Function

View graph for
Biological Process

View graph for
Cellular Component
External links
PDB RCSB:6ip6, PDBe:6ip6, PDBj:6ip6
PDBsum6ip6
PubMed31080011
UniProtP62891|RL39_HUMAN Large ribosomal subunit protein eL39 (Gene Name=RPL39)

[Back to BioLiP]