Structure of PDB 6ip6 Chain 2f
Receptor sequence
>6ip62f (length=50) Species:
9606
(Homo sapiens) [
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SSHKTFRIKRFLAKKQKQNRPIPQWIRMKTGNKIRYNSKRRHWRRTKLGL
3D structure
PDB
6ip6
HCV IRES Captures an Actively Translating 80S Ribosome.
Chain
2f
Resolution
4.5 Å
3D
structure
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Enzymatic activity
Enzyme Commision number
?
Interaction with ligand
Site
#
Ligand
Ligand
chain
Binding residues on receptor
(original residue number in PDB)
Binding residues on receptor
(residue number reindexed from 1)
Binding affinity
BS01
rna
2f
S2 S3 H4 K5 K10 L13 Q17 K34 I35 R36 N38 S39 R41 R42 H43 W44 R45 T47 K48 L49
S1 S2 H3 K4 K9 L12 Q16 K33 I34 R35 N37 S38 R40 R41 H42 W43 R44 T46 K47 L48
BS02
rna
2f
F7 R8 R11 K15 K18 Q19 I23 P24 W26 M29 T31 K40
F6 R7 R10 K14 K17 Q18 I22 P23 W25 M28 T30 K39
Gene Ontology
Molecular Function
GO:0003723
RNA binding
GO:0003735
structural constituent of ribosome
Biological Process
GO:0002181
cytoplasmic translation
GO:0002227
innate immune response in mucosa
GO:0006412
translation
GO:0019731
antibacterial humoral response
GO:0050830
defense response to Gram-positive bacterium
GO:0061844
antimicrobial humoral immune response mediated by antimicrobial peptide
Cellular Component
GO:0005615
extracellular space
GO:0005737
cytoplasm
GO:0005829
cytosol
GO:0005840
ribosome
GO:0022625
cytosolic large ribosomal subunit
GO:0022626
cytosolic ribosome
GO:1990904
ribonucleoprotein complex
View graph for
Molecular Function
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Biological Process
View graph for
Cellular Component
External links
PDB
RCSB:6ip6
,
PDBe:6ip6
,
PDBj:6ip6
PDBsum
6ip6
PubMed
31080011
UniProt
P62891
|RL39_HUMAN Large ribosomal subunit protein eL39 (Gene Name=RPL39)
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