Structure of PDB 8vtu Chain 2c

Receptor sequence
>8vtu2c (length=206) Species: 300852 (Thermus thermophilus HB8) [Search protein sequence]
GNKIHPIGFRLGITRDWESRWYAGKKQYRHLLLEDQRIRGLLEKELYSAG
LARVDIERAADNVAVTVHVAKPGVVIGRGGERIRVLREELAKLTGKNVAL
NVQEVQNPNLSAPLVAQRVAEQIERRFAVRRAIKQAVQRVMESGAKGAKV
IVSGRIGGAEQARTEWAAQGRVPLHTLRANIDYGFALARTTYGVLGVKAY
IFLGEV
3D structure
PDB8vtu Macrolones target bacterial ribosomes and DNA gyrase and can evade resistance mechanisms.
Chain2c
Resolution2.4 Å
3D
structure
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Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 rna 2c G2 N3 K4 I5 F10 K26 S154 G155 R156 E161 Q162 A163 W167 R172 V173 P174 L175 H176 T177 L178 R179 T192 Y193 G194 V195 G1 N2 K3 I4 F9 K25 S153 G154 R155 E160 Q161 A162 W166 R171 V172 P173 L174 H175 T176 L177 R178 T191 Y192 G193 V194
External links
PDB RCSB:8vtu, PDBe:8vtu, PDBj:8vtu
PDBsum8vtu
PubMed39039256
UniProtP80372|RS3_THET8 Small ribosomal subunit protein uS3 (Gene Name=rpsC)

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