Structure of PDB 6xqe Chain 2c

Receptor sequence
>6xqe2c (length=206) Species: 300852 (Thermus thermophilus HB8) [Search protein sequence]
GNKIHPIGFRLGITRDWESRWYAGKKQYRHLLLEDQRIRGLLEKELYSAG
LARVDIERAADNVAVTVHVAKPGVVIGRGGERIRVLREELAKLTGKNVAL
NVQEVQNPNLSAPLVAQRVAEQIERRFAVRRAIKQAVQRVMESGAKGAKV
IVSGRIGGAEQARTEWAAQGRVPLHTLRANIDYGFALARTTYGVLGVKAY
IFLGEV
3D structure
PDB6xqe Sarecycline interferes with tRNA accommodation and tethers mRNA to the 70S ribosome.
Chain2c
Resolution3.0 Å
3D
structure
[Spin on]
[Spin off]
[Reset orientation]

[High quality]
[Low quality]

[White background]
[Black background]

[Download]
[Download structure with residue number starting from 1]
Enzymatic activity
Enzyme Commision number ?
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 rna 2c G2 N3 K4 I5 F10 I14 K26 K150 S154 R156 E161 A163 W167 R172 V173 L175 H176 T177 L178 R179 T192 Y193 G194 V195 K199 G1 N2 K3 I4 F9 I13 K25 K149 S153 R155 E160 A162 W166 R171 V172 L174 H175 T176 L177 R178 T191 Y192 G193 V194 K198
Gene Ontology
Molecular Function
GO:0003676 nucleic acid binding
GO:0003723 RNA binding
GO:0003729 mRNA binding
GO:0003735 structural constituent of ribosome
GO:0019843 rRNA binding
Biological Process
GO:0006412 translation
Cellular Component
GO:0005840 ribosome
GO:0022627 cytosolic small ribosomal subunit
GO:1990904 ribonucleoprotein complex

View graph for
Molecular Function
View graph for
Biological Process
View graph for
Cellular Component
External links
PDB RCSB:6xqe, PDBe:6xqe, PDBj:6xqe
PDBsum6xqe
PubMed32817463
UniProtP80372|RS3_THET8 Small ribosomal subunit protein uS3 (Gene Name=rpsC)

[Back to BioLiP]