Structure of PDB 6ip6 Chain 2b

Receptor sequence
>6ip62b (length=122) Species: 9606 (Homo sapiens) [Search protein sequence]
AKIKARDLRGKKKEELLKQLDDLKVELSQLRVAKVTGGAASKLSKIRVVR
KSIARVLTVINQTQKENLRKFYKGKKYKPLDLRPKKTRAMRRRLNKHEEN
LKTKKQQRKERLYPLRKYAVKA
3D structure
PDB6ip6 HCV IRES Captures an Actively Translating 80S Ribosome.
Chain2b
Resolution4.5 Å
3D
structure
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Enzymatic activity
Enzyme Commision number ?
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 rna 2b K76 K77 K79 R89 R93 H98 K106 R109 R112 K75 K76 K78 R88 R92 H97 K105 R108 R111
BS02 rna 2b A6 R7 K35 A41 L44 S45 R51 K52 A55 R56 L58 T59 N62 Q63 K66 K86 T88 R89 R92 A5 R6 K34 A40 L43 S44 R50 K51 A54 R55 L57 T58 N61 Q62 K65 K85 T87 R88 R91
Gene Ontology
Molecular Function
GO:0003723 RNA binding
GO:0003729 mRNA binding
GO:0003735 structural constituent of ribosome
Biological Process
GO:0000463 maturation of LSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)
GO:0002181 cytoplasmic translation
GO:0006412 translation
Cellular Component
GO:0005730 nucleolus
GO:0005737 cytoplasm
GO:0005829 cytosol
GO:0005840 ribosome
GO:0016020 membrane
GO:0022625 cytosolic large ribosomal subunit
GO:0022626 cytosolic ribosome
GO:1990904 ribonucleoprotein complex

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Cellular Component
External links
PDB RCSB:6ip6, PDBe:6ip6, PDBj:6ip6
PDBsum6ip6
PubMed31080011
UniProtP42766|RL35_HUMAN Large ribosomal subunit protein uL29 (Gene Name=RPL35)

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