Structure of PDB 9b00 Chain 2Z

Receptor sequence
>9b002Z (length=160) Species: 300852 (Thermus thermophilus HB8) [Search protein sequence]
MEYRLKAYYREGEKPSALRRAGKLPGVMYNRHLNRKVYVDLVEFDKVFRQ
ASIHHVIVLELPDGQSLPTLVRQVNLDKRRRRPEHVDFFVLSDEPVEMYV
PLRFVGHRDILVKVSPRNIPEFIEVDVSGLEIGDSLHASDLKLPPGVELA
VSPEETIAAV
3D structure
PDB9b00 Berberine analog of chloramphenicol exhibits a distinct mode of action and unveils ribosome plasticity.
Chain2Z
Resolution2.8 Å
3D
structure
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Interaction with ligand
Site
#
Ligand Ligand
chain
Binding residues on receptor
(original residue number in PDB)
Binding residues on receptor
(residue number reindexed from 1)
Binding affinity
BS01 rna 2Z K46 S149 E169 T170 K46 S135 E155 T156
BS02 rna 2Z R10 P15 R19 Y29 N30 N34 R72 Q73 R79 H85 D87 R10 P15 R19 Y29 N30 N34 R72 Q73 R79 H85 D87
BS03 MG 2Z M1 H55 V56 M1 H55 V56
External links
PDB RCSB:9b00, PDBe:9b00, PDBj:9b00
PDBsum9b00
PubMed39019034
UniProtQ5SHZ1|RL25_THET8 Large ribosomal subunit protein bL25 (Gene Name=rplY)

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