Structure of PDB 8vtu Chain 2Z

Receptor sequence
>8vtu2Z (length=160) Species: 300852 (Thermus thermophilus HB8) [Search protein sequence]
MEYRLKAYYREGEKPSALRRAGKLPGVMYNRHLNRKVYVDLVEFDKVFRQ
ASIHHVIVLELPDGQSLPTLVRQVNLDKRRRRPEHVDFFVLSDEPVEMYV
PLRFVGHRDILVKVSPRNIPEFIEVDVSGLEIGDSLHASDLKLPPGVELA
VSPEETIAAV
3D structure
PDB8vtu Macrolones target bacterial ribosomes and DNA gyrase and can evade resistance mechanisms.
Chain2Z
Resolution2.4 Å
3D
structure
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Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 rna 2Z E169 T170 E155 T156
BS02 rna 2Z R10 R19 Y29 N30 R31 N34 R72 Q73 R79 E84 H85 D87 R10 R19 Y29 N30 R31 N34 R72 Q73 R79 E84 H85 D87
External links
PDB RCSB:8vtu, PDBe:8vtu, PDBj:8vtu
PDBsum8vtu
PubMed39039256
UniProtQ5SHZ1|RL25_THET8 Large ribosomal subunit protein bL25 (Gene Name=rplY)

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