Structure of PDB 6xhv Chain 2Z

Receptor sequence
>6xhv2Z (length=160) Species: 300852 (Thermus thermophilus HB8) [Search protein sequence]
MEYRLKAYYREGEKPSALRRAGKLPGVMYNRHLNRKVYVDLVEFDKVFRQ
ASIHHVIVLELPDGQSLPTLVRQVNLDKRRRRPEHVDFFVLSDEPVEMYV
PLRFVGHRDILVKVSPRNIPEFIEVDVSGLEIGDSLHASDLKLPPGVELA
VSPEETIAAV
3D structure
PDB6xhv Structure of Erm-modified 70S ribosome reveals the mechanism of macrolide resistance.
Chain2Z
Resolution2.4 Å
3D
structure
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Enzymatic activity
Enzyme Commision number ?
Interaction with ligand
Site
#
Ligand Ligand
chain
Binding residues on receptor
(original residue number in PDB)
Binding residues on receptor
(residue number reindexed from 1)
Binding affinity
BS01 rna 2Z H151 E169 T170 H137 E155 T156
BS02 rna 2Z R10 R19 V27 Y29 R31 N34 R72 Q73 R79 E84 H85 D87 R10 R19 V27 Y29 R31 N34 R72 Q73 R79 E84 H85 D87
BS03 MG 2Z M1 H55 V56 M1 H55 V56
Gene Ontology
Molecular Function
GO:0003723 RNA binding
GO:0003735 structural constituent of ribosome
GO:0008097 5S rRNA binding
GO:0019843 rRNA binding
Biological Process
GO:0006412 translation
Cellular Component
GO:0005840 ribosome
GO:0022625 cytosolic large ribosomal subunit
GO:1990904 ribonucleoprotein complex

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Molecular Function

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Cellular Component
External links
PDB RCSB:6xhv, PDBe:6xhv, PDBj:6xhv
PDBsum6xhv
PubMed33462493
UniProtQ5SHZ1|RL25_THET8 Large ribosomal subunit protein bL25 (Gene Name=rplY)

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