Structure of PDB 5w4k Chain 2Z

Receptor sequence
>5w4k2Z (length=160) Species: 300852 (Thermus thermophilus HB8) [Search protein sequence]
MEYRLKAYYREGEKPSALRRAGKLPGVMYNRHLNRKVYVDLVEFDKVFRQ
ASIHHVIVLELPDGQSLPTLVRQVNLDKRRRRPEHVDFFVLSDEPVEMYV
PLRFVGHRDILVKVSPRNIPEFIEVDVSGLEIGDSLHASDLKLPPGVELA
VSPEETIAAV
3D structure
PDB5w4k Klebsazolicin inhibits 70S ribosome by obstructing the peptide exit tunnel.
Chain2Z
Resolution2.7 Å
3D
structure
[Spin on]
[Spin off]
[Reset orientation]

[High quality]
[Low quality]

[White background]
[Black background]

[Download]
[Download structure with residue number starting from 1]
Enzymatic activity
Enzyme Commision number ?
Interaction with ligand
Site
#
Ligand Ligand
chain
Binding residues on receptor
(original residue number in PDB)
Binding residues on receptor
(residue number reindexed from 1)
Binding affinity
BS01 rna 2Z E169 T170 E155 T156
BS02 rna 2Z R10 K14 R19 V27 Y29 N30 R31 N34 R72 Q73 N75 R79 E84 H85 D87 R10 K14 R19 V27 Y29 N30 R31 N34 R72 Q73 N75 R79 E84 H85 D87
BS03 MG 2Z M1 H55 V56 M1 H55 V56
Gene Ontology
Molecular Function
GO:0003723 RNA binding
GO:0003735 structural constituent of ribosome
GO:0008097 5S rRNA binding
GO:0019843 rRNA binding
Biological Process
GO:0006412 translation
Cellular Component
GO:0005840 ribosome
GO:0022625 cytosolic large ribosomal subunit
GO:1990904 ribonucleoprotein complex

View graph for
Molecular Function

View graph for
Biological Process

View graph for
Cellular Component
External links
PDB RCSB:5w4k, PDBe:5w4k, PDBj:5w4k
PDBsum5w4k
PubMed28846667
UniProtQ5SHZ1|RL25_THET8 Large ribosomal subunit protein bL25 (Gene Name=rplY)

[Back to BioLiP]