Structure of PDB 8ekb Chain 2Y

Receptor sequence
>8ekb2Y (length=107) Species: 300852 (Thermus thermophilus HB8) [Search protein sequence]
MRVKMHVKKGDTVLVASGKYKGRVGKVKEVLPKKYAVIVEGVNIVKKAVR
VSPKYPQGGFIEKEAPLHASKVRPICPACGKPTRVRKKFLENGKKIRVCA
KCGGALD
3D structure
PDB8ekb Insights into the molecular mechanism of translation inhibition by the ribosome-targeting antibiotic thermorubin.
Chain2Y
Resolution2.7 Å
3D
structure
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Enzymatic activity
Enzyme Commision number ?
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 rna 2Y M1 R2 K4 H6 K8 S17 G18 K19 K21 V30 P32 K46 K47 A48 V49 V51 G59 F60 H68 S70 K71 R73 R84 R86 K87 K95 K101 M1 R2 K4 H6 K8 S17 G18 K19 K21 V30 P32 K46 K47 A48 V49 V51 G59 F60 H68 S70 K71 R73 R84 R86 K87 K95 K101
BS02 ZN 2Y C76 C79 C99 C102 C76 C79 C99 C102
Gene Ontology
Molecular Function
GO:0003723 RNA binding
GO:0003735 structural constituent of ribosome
GO:0019843 rRNA binding
Biological Process
GO:0006412 translation
Cellular Component
GO:0005840 ribosome
GO:1990904 ribonucleoprotein complex

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Cellular Component
External links
PDB RCSB:8ekb, PDBe:8ekb, PDBj:8ekb
PDBsum8ekb
PubMed36546783
UniProtQ5SHP9|RL24_THET8 Large ribosomal subunit protein uL24 (Gene Name=rplX)

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