Structure of PDB 6of1 Chain 2Y

Receptor sequence

>6of12Y (length=107) Species: 300852 (Thermus thermophilus HB8) [Search protein sequence]

MRVKMHVKKGDTVLVASGKYKGRVGKVKEVLPKKYAVIVEGVNIVKKAVR
VSPKYPQGGFIEKEAPLHASKVRPICPACGKPTRVRKKFLENGKKIRVCA
KCGGALD

3D structure

PDB

6of1 Structure of Dirithromycin Bound to the Bacterial Ribosome Suggests New Ways for Rational Improvement of Macrolides.

Chain

Resolution

2.8 Å

3D
structure

Enzymatic activity

Enzyme Commision number

Interaction with ligand

Site #	Ligand	Ligand chain	Binding residues on receptor (original residue number in PDB)	Binding residues on receptor (residue number reindexed from 1)	Binding affinity
BS01	rna	2Y	M1 K4 H6 K8 K9 S17 G18 K19 K21 V30 P32 Y35 K46 K47 A48 V49 G58 G59 F60 K63 H68 S70 K71 R73 R84 R86 K87 K95 K101	M1 K4 H6 K8 K9 S17 G18 K19 K21 V30 P32 Y35 K46 K47 A48 V49 G58 G59 F60 K63 H68 S70 K71 R73 R84 R86 K87 K95 K101
BS02	ZN	2Y	C76 C79 C99 C102	C76 C79 C99 C102

Gene Ontology

	Molecular Function
GO:0003723	RNA binding
GO:0003735	structural constituent of ribosome
GO:0019843	rRNA binding

	Biological Process
GO:0006412	translation

	Cellular Component
GO:0005840	ribosome
GO:1990904	ribonucleoprotein complex

External links

PDB	RCSB:6of1, PDBe:6of1, PDBj:6of1
PDBsum	6of1
PubMed	30936109
UniProt	Q5SHP9\|RL24_THET8 Large ribosomal subunit protein uL24 (Gene Name=rplX)