Structure of PDB 5hau Chain 2Y

Receptor sequence

>5hau2Y (length=76) Species: 300852 (Thermus thermophilus HB8)

GTRNGRDSQAKRLGVKRYEGQVVRAGNILVRQRGTRFKPGKNVGMGRDFT
LFALVDGVVEFQDRGRLGRYVHVRPL

3D structure

• PDB: 5hau Structures of proline-rich peptides bound to the ribosome reveal a common mechanism of protein synthesis inhibition.
• Chain: 2Y
• Resolution: 3.0 Å

Interaction with ligand

Site #	Ligand	Ligand chain	Binding residues on receptor (original residue number in PDB)	Binding residues on receptor (residue number reindexed from 1)	Binding affinity
BS01	rna	2Y	T10 R11 N12 R14 D15 S16 Q17 A18 K19 R20 K24 Y26 E27 Q29 R32 A33 G34 N35 I36 R39 R41 G42 T43 R44 G54 R55 D56 F57 T58 F60 F69 R74 L75 R77	T2 R3 N4 R6 D7 S8 Q9 A10 K11 R12 K16 Y18 E19 Q21 R24 A25 G26 N27 I28 R31 R33 G34 T35 R36 G46 R47 D48 F49 T50 F52 F61 R66 L67 R69
BS02	rna	2Y	R72 G73 R74	R64 G65 R66

Gene Ontology

Molecular Function

• GO:0003735 structural constituent of ribosome

Biological Process

• GO:0006412 translation

Cellular Component

• GO:0005840 ribosome
• GO:0022625 cytosolic large ribosomal subunit
• GO:1990904 ribonucleoprotein complex

External links

• PDB: RCSB:5hau, PDBe:5hau, PDBj:5hau
• PDBsum: 5hau
• PubMed: 26809677
• UniProt: P60493|RL27_THET8 Large ribosomal subunit protein bL27 (Gene Name=rpmA)