Structure of PDB 8vtv Chain 2X

Receptor sequence
>8vtv2X (length=95) Species: 300852 (Thermus thermophilus HB8) [Search protein sequence]
MKTAYDVILAPVLSEKAYAGFAEGKYTFWVHPKATKTEIKNAVETAFKVK
VVKVNTLHVRGKKKRLGRYLGKRPDRKKAIVQVAPGQKIEALEGL
3D structure
PDB8vtv Macrolones target bacterial ribosomes and DNA gyrase and can evade resistance mechanisms.
Chain2X
Resolution2.55 Å
3D
structure
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Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 rna 2X K2 S14 K16 K25 H31 T35 K36 T37 E38 K40 K53 N55 L57 H58 R60 K62 K63 K64 R65 L66 Y69 G71 K72 R73 P74 D75 K78 I80 K2 S14 K16 K25 H31 T35 K36 T37 E38 K40 K53 N55 L57 H58 R60 K62 K63 K64 R65 L66 Y69 G71 K72 R73 P74 D75 K78 I80
BS02 MG 2X A17 T27 A17 T27
External links
PDB RCSB:8vtv, PDBe:8vtv, PDBj:8vtv
PDBsum8vtv
PubMed39039256
UniProtQ5SHP0|RL23_THET8 Large ribosomal subunit protein uL23 (Gene Name=rplW)

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