Structure of PDB 6xqe Chain 2X

Receptor sequence
>6xqe2X (length=95) Species: 300852 (Thermus thermophilus HB8) [Search protein sequence]
MKTAYDVILAPVLSEKAYAGFAEGKYTFWVHPKATKTEIKNAVETAFKVK
VVKVNTLHVRGKKKRLGRYLGKRPDRKKAIVQVAPGQKIEALEGL
3D structure
PDB6xqe Sarecycline interferes with tRNA accommodation and tethers mRNA to the 70S ribosome.
Chain2X
Resolution3.0 Å
3D
structure
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Enzymatic activity
Enzyme Commision number ?
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 rna 2X K2 S14 K16 K25 H31 T35 K36 T37 E38 N41 K53 N55 T56 L57 H58 R60 K64 Y69 L70 G71 K72 R73 P74 K77 K78 I80 K2 S14 K16 K25 H31 T35 K36 T37 E38 N41 K53 N55 T56 L57 H58 R60 K64 Y69 L70 G71 K72 R73 P74 K77 K78 I80
Gene Ontology
Molecular Function
GO:0003735 structural constituent of ribosome
GO:0019843 rRNA binding
Biological Process
GO:0000027 ribosomal large subunit assembly
GO:0006412 translation
Cellular Component
GO:0005840 ribosome
GO:0022625 cytosolic large ribosomal subunit
GO:1990904 ribonucleoprotein complex

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Molecular Function
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Cellular Component
External links
PDB RCSB:6xqe, PDBe:6xqe, PDBj:6xqe
PDBsum6xqe
PubMed32817463
UniProtQ5SHP0|RL23_THET8 Large ribosomal subunit protein uL23 (Gene Name=rplW)

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