Structure of PDB 5vp2 Chain 2X

Receptor sequence
>5vp22X (length=95) Species: 300852 (Thermus thermophilus HB8) [Search protein sequence]
MKTAYDVILAPVLSEKAYAGFAEGKYTFWVHPKATKTEIKNAVETAFKVK
VVKVNTLHVRGKKKRLGRYLGKRPDRKKAIVQVAPGQKIEALEGL
3D structure
PDB5vp2 Madumycin II inhibits peptide bond formation by forcing the peptidyl transferase center into an inactive state.
Chain2X
Resolution2.8 Å
3D
structure
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Enzymatic activity
Enzyme Commision number ?
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 rna 2X K2 S14 K16 K25 T35 K36 T37 E38 K40 K53 N55 T56 L57 H58 R60 K62 K63 K64 R65 Y69 L70 G71 K72 R73 P74 K78 I80 K2 S14 K16 K25 T35 K36 T37 E38 K40 K53 N55 T56 L57 H58 R60 K62 K63 K64 R65 Y69 L70 G71 K72 R73 P74 K78 I80
BS02 MG 2X A17 K25 Y26 T27 A17 K25 Y26 T27
Gene Ontology
Molecular Function
GO:0003735 structural constituent of ribosome
GO:0019843 rRNA binding
Biological Process
GO:0000027 ribosomal large subunit assembly
GO:0006412 translation
Cellular Component
GO:0005840 ribosome
GO:0022625 cytosolic large ribosomal subunit
GO:1990904 ribonucleoprotein complex

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Biological Process
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Cellular Component
External links
PDB RCSB:5vp2, PDBe:5vp2, PDBj:5vp2
PDBsum5vp2
PubMed28505372
UniProtQ5SHP0|RL23_THET8 Large ribosomal subunit protein uL23 (Gene Name=rplW)

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