Structure of PDB 8vty Chain 2V

Receptor sequence
>8vty2V (length=101) Species: 300852 (Thermus thermophilus HB8) [Search protein sequence]
MFAIVKTGGKQYRVEPGLKLRVEKLDAEPGATVELPVLLLGGEKTVVGTP
VVEGASVVAEVLGHGRGKKILVSKFKAKVQYRRKKGHRQPYTELLIKEIR
G
3D structure
PDB8vty Macrolones target bacterial ribosomes and DNA gyrase and can evade resistance mechanisms.
Chain2V
Resolution2.6 Å
3D
structure
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Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 rna 2V G8 G9 K10 E23 K24 R66 K69 K74 F75 K76 A77 K78 V79 Q80 Y81 K84 K85 G86 H87 Q89 G8 G9 K10 E23 K24 R66 K69 K74 F75 K76 A77 K78 V79 Q80 Y81 K84 K85 G86 H87 Q89
BS02 MG 2V K24 P90 K24 P90
BS03 MG 2V F75 K76 Q80 R82 F75 K76 Q80 R82
External links
PDB RCSB:8vty, PDBe:8vty, PDBj:8vty
PDBsum8vty
PubMed39039256
UniProtP60492|RL21_THET8 Large ribosomal subunit protein bL21 (Gene Name=rplU)

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