Structure of PDB 9b00 Chain 2T

Receptor sequence

>9b002T (length=131) Species: 300852 (Thermus thermophilus HB8) [Search protein sequence]

MNRGALIKLVESRYVRTDLPEFRPGDTVRVSYKVKEGNRTRIQDFEGIVI
RIRRNGFNTTFTVRKVSYGVGVERIFPLHSPLIQKIDIVQRGRARRAKLY
FIRNLSDREIRRKLRADRKRIDQDRAAERAA

3D structure

PDB

9b00 Berberine analog of chloramphenicol exhibits a distinct mode of action and unveils ribosome plasticity.

Chain

Resolution

2.8 Å

3D
structure

Interaction with ligand

Site #	Ligand	Ligand chain	Binding residues on receptor (original residue number in PDB)	Binding residues on receptor (residue number reindexed from 1)
BS01	rna	2T	M1 N2 R3 G4 R23 R51 R53 R54 N55 N58 T60 I75 R95 R96 A97 K98 Y100 F101 K113 R115 K119	M1 N2 R3 G4 R23 R51 R53 R54 N55 N58 T60 I75 R95 R96 A97 K98 Y100 F101 K113 R115 K119
BS02	rna	2T	R39 R41 Q43 S106 R108 R118 D122 R125	R39 R41 Q43 S106 R108 R118 D122 R125
BS03	MG	2T	I52 A97 K98	I52 A97 K98

External links

PDB	RCSB:9b00, PDBe:9b00, PDBj:9b00
PDBsum	9b00
PubMed	39019034
UniProt	P60490\|RL19_THET8 Large ribosomal subunit protein bL19 (Gene Name=rplS)