Structure of PDB 8vtw Chain 2T

Receptor sequence
>8vtw2T (length=131) Species: 300852 (Thermus thermophilus HB8) [Search protein sequence]
MNRGALIKLVESRYVRTDLPEFRPGDTVRVSYKVKEGNRTRIQDFEGIVI
RIRRNGFNTTFTVRKVSYGVGVERIFPLHSPLIQKIDIVQRGRARRAKLY
FIRNLSDREIRRKLRADRKRIDQDRAAERAA
3D structure
PDB8vtw Macrolones target bacterial ribosomes and DNA gyrase and can evade resistance mechanisms.
Chain2T
Resolution2.35 Å
3D
structure
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Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 rna 2T N2 R3 G4 R23 R51 R53 R54 N55 N58 T60 I75 R93 R95 R96 A97 K98 Y100 F101 K113 K119 N2 R3 G4 R23 R51 R53 R54 N55 N58 T60 I75 R93 R95 R96 A97 K98 Y100 F101 K113 K119
BS02 rna 2T R39 R41 Q43 S106 R108 R118 K119 D122 R39 R41 Q43 S106 R108 R118 K119 D122
External links
PDB RCSB:8vtw, PDBe:8vtw, PDBj:8vtw
PDBsum8vtw
PubMed39039256
UniProtP60490|RL19_THET8 Large ribosomal subunit protein bL19 (Gene Name=rplS)

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