Structure of PDB 8vtv Chain 2T

Receptor sequence
>8vtv2T (length=131) Species: 300852 (Thermus thermophilus HB8) [Search protein sequence]
MNRGALIKLVESRYVRTDLPEFRPGDTVRVSYKVKEGNRTRIQDFEGIVI
RIRRNGFNTTFTVRKVSYGVGVERIFPLHSPLIQKIDIVQRGRARRAKLY
FIRNLSDREIRRKLRADRKRIDQDRAAERAA
3D structure
PDB8vtv Macrolones target bacterial ribosomes and DNA gyrase and can evade resistance mechanisms.
Chain2T
Resolution2.55 Å
3D
structure
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Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 rna 2T M1 N2 R3 G4 R23 R51 R53 R54 N58 T60 I75 R93 R95 R96 A97 K98 F101 K113 K119 M1 N2 R3 G4 R23 R51 R53 R54 N58 T60 I75 R93 R95 R96 A97 K98 F101 K113 K119
BS02 rna 2T R39 R41 S106 R108 R118 K119 R125 R39 R41 S106 R108 R118 K119 R125
BS03 MG 2T I52 K98 I52 K98
External links
PDB RCSB:8vtv, PDBe:8vtv, PDBj:8vtv
PDBsum8vtv
PubMed39039256
UniProtP60490|RL19_THET8 Large ribosomal subunit protein bL19 (Gene Name=rplS)

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