Structure of PDB 6ip6 Chain 2C

Receptor sequence
>6ip62C (length=190) Species: 9606 (Homo sapiens) [Search protein sequence]
MKTILSNQTVDIPENVDITLKGRTVIVKGPRGTLRRDFNHINVELSLLGK
KKKRLRVDKWWGNRKELATVRTICSHVQNMIKGVTLGFRYKMRSVYAHFP
INVVIQENGSLVEIRNFLGEKYIRRVRMRPGVACSVSQAQKDELILEGND
IELVSNSAALIQQATTVKNKDIRKFLDGIYVSEKGTVQQA
3D structure
PDB6ip6 HCV IRES Captures an Actively Translating 80S Ribosome.
Chain2C
Resolution4.5 Å
3D
structure
[Spin on]
[Spin off]
[Reset orientation]

[High quality]
[Low quality]

[White background]
[Black background]

[Download]
[Download structure with residue number starting from 1]
Enzymatic activity
Enzyme Commision number ?
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 rna 2C M1 R23 H40 N42 V43 E44 K59 R64 A68 R71 T72 S75 N79 H98 F99 L118 E120 Y122 R129 E152 S155 Q163 K168 K170 D171 R173 M1 R23 H40 N42 V43 E44 K59 R64 A68 R71 T72 S75 N79 H98 F99 L118 E120 Y122 R129 E152 S155 Q163 K168 K170 D171 R173
Gene Ontology
Molecular Function
GO:0003723 RNA binding
GO:0003735 structural constituent of ribosome
GO:0005515 protein binding
GO:0019843 rRNA binding
Biological Process
GO:0002181 cytoplasmic translation
GO:0006412 translation
Cellular Component
GO:0005634 nucleus
GO:0005737 cytoplasm
GO:0005829 cytosol
GO:0005840 ribosome
GO:0005925 focal adhesion
GO:0016020 membrane
GO:0022625 cytosolic large ribosomal subunit
GO:0022626 cytosolic ribosome
GO:1990904 ribonucleoprotein complex

View graph for
Molecular Function
View graph for
Biological Process
View graph for
Cellular Component
External links
PDB RCSB:6ip6, PDBe:6ip6, PDBj:6ip6
PDBsum6ip6
PubMed31080011
UniProtP32969|RL9_HUMAN Large ribosomal subunit protein uL6 (Gene Name=RPL9)

[Back to BioLiP]