Structure of PDB 8vtw Chain 29

Receptor sequence
>8vtw29 (length=37) Species: 300852 (Thermus thermophilus HB8) [Search protein sequence]
MKVRASVKRICDKCKVIRRHGRVYVICENPKHKQRQG
3D structure
PDB8vtw Macrolones target bacterial ribosomes and DNA gyrase and can evade resistance mechanisms.
Chain29
Resolution2.35 Å
3D
structure
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Interaction with ligand
Site
#
Ligand Ligand
chain
Binding residues on receptor
(original residue number in PDB)
Binding residues on receptor
(residue number reindexed from 1)
Binding affinity
BS01 rna 29 M1 K2 R4 A5 S6 V7 I10 V16 R18 R19 H20 P30 K31 K33 R35 Q36 M1 K2 R4 A5 S6 V7 I10 V16 R18 R19 H20 P30 K31 K33 R35 Q36
BS02 ZN 29 C11 C14 C27 H32 C11 C14 C27 H32
External links
PDB RCSB:8vtw, PDBe:8vtw, PDBj:8vtw
PDBsum8vtw
PubMed39039256
UniProtQ5SHR2|RL36_THET8 Large ribosomal subunit protein bL36 (Gene Name=rpmJ)

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