Structure of PDB 8vtv Chain 26
Receptor sequence
>8vtv26 (length=53) Species:
300852
(Thermus thermophilus HB8) [
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ASEVRIKLLLECTECKRRNYATEKNKRNTPNKLELRKYCPWCRKHTVHRE
VKI
3D structure
PDB
8vtv
Macrolones target bacterial ribosomes and DNA gyrase and can evade resistance mechanisms.
Chain
26
Resolution
2.55 Å
3D
structure
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Interaction with ligand
Site
#
Ligand
Ligand
chain
Binding residues on receptor
(original residue number in PDB)
Binding residues on receptor
(residue number reindexed from 1)
Binding affinity
BS01
rna
26
A2 S3 R6 R18 R19 Y21 E24 K25 N26 N29 L36 R37 K38 Y39 P41 W42 R44 H46 I54
A1 S2 R5 R17 R18 Y20 E23 K24 N25 N28 L35 R36 K37 Y38 P40 W41 R43 H45 I53
BS02
MG
26
R6 E24 K25
R5 E23 K24
BS03
ZN
26
C13 C16 C40 C43
C12 C15 C39 C42
External links
PDB
RCSB:8vtv
,
PDBe:8vtv
,
PDBj:8vtv
PDBsum
8vtv
PubMed
39039256
UniProt
P35871
|RL33_THET8 Large ribosomal subunit protein bL33 (Gene Name=rpmG)
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