Structure of PDB 8vtu Chain 26

Receptor sequence
>8vtu26 (length=53) Species: 300852 (Thermus thermophilus HB8) [Search protein sequence]
ASEVRIKLLLECTECKRRNYATEKNKRNTPNKLELRKYCPWCRKHTVHRE
VKI
3D structure
PDB8vtu Macrolones target bacterial ribosomes and DNA gyrase and can evade resistance mechanisms.
Chain26
Resolution2.4 Å
3D
structure
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Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 rna 26 A2 S3 R6 R18 R19 Y21 E24 K25 N26 N29 T30 L34 R37 K38 Y39 P41 W42 R44 H46 I54 A1 S2 R5 R17 R18 Y20 E23 K24 N25 N28 T29 L33 R36 K37 Y38 P40 W41 R43 H45 I53
BS02 MG 26 R6 E24 R5 E23
BS03 ZN 26 C13 C16 C40 C43 C12 C15 C39 C42
External links
PDB RCSB:8vtu, PDBe:8vtu, PDBj:8vtu
PDBsum8vtu
PubMed39039256
UniProtP35871|RL33_THET8 Large ribosomal subunit protein bL33 (Gene Name=rpmG)

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