Structure of PDB 8fc3 Chain 26
Receptor sequence
>8fc326 (length=53) Species:
300852
(Thermus thermophilus HB8) [
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ASEVRIKLLLECTECKRRNYATEKNKRNTPNKLELRKYCPWCRKHTVHRE
VKI
3D structure
PDB
8fc3
Structural insights into the mechanism of overcoming Erm-mediated resistance by macrolides acting together with hygromycin-A.
Chain
26
Resolution
2.6 Å
3D
structure
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Enzymatic activity
Enzyme Commision number
?
Interaction with ligand
Site
#
Ligand
Ligand
chain
Binding residues on receptor
(original residue number in PDB)
Binding residues on receptor
(residue number reindexed from 1)
Binding affinity
BS01
rna
26
A2 S3 R6 K8 R18 Y21 T23 E24 N26 N29 L34 L36 R37 K38 Y39 W42 R44 H46 I54
A1 S2 R5 K7 R17 Y20 T22 E23 N25 N28 L33 L35 R36 K37 Y38 W41 R43 H45 I53
BS02
MG
26
R6 E24
R5 E23
BS03
ZN
26
C13 C16 C40 C43
C12 C15 C39 C42
Gene Ontology
Molecular Function
GO:0000049
tRNA binding
GO:0003735
structural constituent of ribosome
GO:0019843
rRNA binding
Biological Process
GO:0006412
translation
Cellular Component
GO:0005737
cytoplasm
GO:0005840
ribosome
GO:1990904
ribonucleoprotein complex
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Molecular Function
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Biological Process
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Cellular Component
External links
PDB
RCSB:8fc3
,
PDBe:8fc3
,
PDBj:8fc3
PDBsum
8fc3
PubMed
37452045
UniProt
P35871
|RL33_THET8 Large ribosomal subunit protein bL33 (Gene Name=rpmG)
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