Structure of PDB 8fc3 Chain 26

Receptor sequence
>8fc326 (length=53) Species: 300852 (Thermus thermophilus HB8) [Search protein sequence]
ASEVRIKLLLECTECKRRNYATEKNKRNTPNKLELRKYCPWCRKHTVHRE
VKI
3D structure
PDB8fc3 Structural insights into the mechanism of overcoming Erm-mediated resistance by macrolides acting together with hygromycin-A.
Chain26
Resolution2.6 Å
3D
structure
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Enzymatic activity
Enzyme Commision number ?
Interaction with ligand
Site
#
Ligand Ligand
chain
Binding residues on receptor
(original residue number in PDB)
Binding residues on receptor
(residue number reindexed from 1)
Binding affinity
BS01 rna 26 A2 S3 R6 K8 R18 Y21 T23 E24 N26 N29 L34 L36 R37 K38 Y39 W42 R44 H46 I54 A1 S2 R5 K7 R17 Y20 T22 E23 N25 N28 L33 L35 R36 K37 Y38 W41 R43 H45 I53
BS02 MG 26 R6 E24 R5 E23
BS03 ZN 26 C13 C16 C40 C43 C12 C15 C39 C42
Gene Ontology
Molecular Function
GO:0000049 tRNA binding
GO:0003735 structural constituent of ribosome
GO:0019843 rRNA binding
Biological Process
GO:0006412 translation
Cellular Component
GO:0005737 cytoplasm
GO:0005840 ribosome
GO:1990904 ribonucleoprotein complex

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Molecular Function

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Cellular Component
External links
PDB RCSB:8fc3, PDBe:8fc3, PDBj:8fc3
PDBsum8fc3
PubMed37452045
UniProtP35871|RL33_THET8 Large ribosomal subunit protein bL33 (Gene Name=rpmG)

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