Structure of PDB 5wit Chain 26
Receptor sequence
>5wit26 (length=53) Species:
300852
(Thermus thermophilus HB8) [
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ASEVRIKLLLECTECKRRNYATEKNKRNTPNKLELRKYCPWCRKHTVHRE
VKI
3D structure
PDB
5wit
Co-produced natural ketolides methymycin and pikromycin inhibit bacterial growth by preventing synthesis of a limited number of proteins.
Chain
26
Resolution
2.6 Å
3D
structure
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Enzymatic activity
Enzyme Commision number
?
Interaction with ligand
Site
#
Ligand
Ligand
chain
Binding residues on receptor
(original residue number in PDB)
Binding residues on receptor
(residue number reindexed from 1)
Binding affinity
BS01
rna
26
S3 R6 K8 R18 R19 Y21 T23 E24 K25 N26 N29 L34 L36 R37 K38 Y39 W42 R44 H46 I54
S2 R5 K7 R17 R18 Y20 T22 E23 K24 N25 N28 L33 L35 R36 K37 Y38 W41 R43 H45 I53
BS02
ZN
26
C13 C16 C40 C43
C12 C15 C39 C42
Gene Ontology
Molecular Function
GO:0000049
tRNA binding
GO:0003735
structural constituent of ribosome
GO:0019843
rRNA binding
Biological Process
GO:0006412
translation
Cellular Component
GO:0005737
cytoplasm
GO:0005840
ribosome
GO:1990904
ribonucleoprotein complex
View graph for
Molecular Function
View graph for
Biological Process
View graph for
Cellular Component
External links
PDB
RCSB:5wit
,
PDBe:5wit
,
PDBj:5wit
PDBsum
5wit
PubMed
28934499
UniProt
P35871
|RL33_THET8 Large ribosomal subunit protein bL33 (Gene Name=rpmG)
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