Structure of PDB 8vtv Chain 23

Receptor sequence
>8vtv23 (length=59) Species: 300852 (Thermus thermophilus HB8) [Search protein sequence]
PRLKVKLVKSPIGYPKDQKAALKALGLRRLQQERVLEDTPAIRGNVEKVA
HLVRVEVVE
3D structure
PDB8vtv Macrolones target bacterial ribosomes and DNA gyrase and can evade resistance mechanisms.
Chain23
Resolution2.55 Å
3D
structure
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Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 rna 23 K10 S11 G14 K17 A21 A22 K24 A25 R30 L31 P41 A42 G45 N46 K49 K9 S10 G13 K16 A20 A21 K23 A24 R29 L30 P40 A41 G44 N45 K48
BS02 MG 23 K10 S11 Y15 K9 S10 Y14
External links
PDB RCSB:8vtv, PDBe:8vtv, PDBj:8vtv
PDBsum8vtv
PubMed39039256
UniProtQ5SHQ6|RL30_THET8 Large ribosomal subunit protein uL30 (Gene Name=rpmD)

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