Structure of PDB 5wis Chain 23

Receptor sequence
>5wis23 (length=59) Species: 300852 (Thermus thermophilus HB8) [Search protein sequence]
PRLKVKLVKSPIGYPKDQKAALKALGLRRLQQERVLEDTPAIRGNVEKVA
HLVRVEVVE
3D structure
PDB5wis Co-produced natural ketolides methymycin and pikromycin inhibit bacterial growth by preventing synthesis of a limited number of proteins.
Chain23
Resolution2.703 Å
3D
structure
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Enzymatic activity
Enzyme Commision number ?
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 rna 23 S11 I13 G14 Y15 P16 K17 D18 A21 A22 K24 A25 R29 R30 L31 P41 A42 G45 N46 K49 S10 I12 G13 Y14 P15 K16 D17 A20 A21 K23 A24 R28 R29 L30 P40 A41 G44 N45 K48
BS02 rna 23 Y15 Q19 H52 Y14 Q18 H51
BS03 MG 23 K17 D18 K16 D17
BS04 MG 23 K10 S11 Y15 K9 S10 Y14
Gene Ontology
Molecular Function
GO:0003735 structural constituent of ribosome
Biological Process
GO:0006412 translation
Cellular Component
GO:0005840 ribosome
GO:0015934 large ribosomal subunit
GO:0022625 cytosolic large ribosomal subunit
GO:1990904 ribonucleoprotein complex

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Cellular Component
External links
PDB RCSB:5wis, PDBe:5wis, PDBj:5wis
PDBsum5wis
PubMed28934499
UniProtQ5SHQ6|RL30_THET8 Large ribosomal subunit protein uL30 (Gene Name=rpmD)

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