Structure of PDB 3j6x Chain 23

Receptor sequence

>3j6x23 (length=144) Species: 580240 (Saccharomyces cerevisiae W303) [Search protein sequence]

GKGKPRGLNSARKLRVHRRNNRWAENNYKKRLLGTAFKSSPFGGSSHAKG
IVLEKLGIESKQPNSAIRKCVRVQLIKNGKKVTAFVPNDGCLNFVDENDE
VLLAGFGRKGKAKGDIPGVRFKVVKVSGVSLLALWKEKKEKPRS

3D structure

PDB

3j6x Taura syndrome virus IRES initiates translation by binding its tRNA-mRNA-like structural element in the ribosomal decoding center.

Chain

Resolution

6.1 Å

3D
structure

Enzymatic activity

Enzyme Commision number

Interaction with ligand

Site #	Ligand	Ligand chain	Binding residues on receptor (original residue number in PDB)	Binding residues on receptor (residue number reindexed from 1)	Binding affinity
BS01	rna	23	K3 G4 P6 R7 N10 R13 K14 R19 R20 N22 R23 W24 A25 E26 R32 F38 S46 S47 H48 K50 K62 Q63 N65 S66 A67 I68 R69 R73 K78 N89 D90 L103 G106 F107 G108 R109 K110 K114 G115 K126 S131 W136	K2 G3 P5 R6 N9 R12 K13 R18 R19 N21 R22 W23 A24 E25 R31 F37 S45 S46 H47 K49 K61 Q62 N64 S65 A66 I67 R68 R72 K77 N88 D89 L102 G105 F106 G107 R108 K109 K113 G114 K125 S130 W135

Gene Ontology

	Molecular Function
GO:0003735	structural constituent of ribosome

	Biological Process
GO:0000462	maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)
GO:0006412	translation
GO:0006450	regulation of translational fidelity
GO:1990145	maintenance of translational fidelity

	Cellular Component
GO:0005737	cytoplasm
GO:0005829	cytosol
GO:0005840	ribosome
GO:0015935	small ribosomal subunit
GO:0022627	cytosolic small ribosomal subunit
GO:1990904	ribonucleoprotein complex

External links

PDB	RCSB:3j6x, PDBe:3j6x, PDBj:3j6x
PDBsum	3j6x
PubMed	24927574
UniProt	P0CX29\|RS23A_YEAST Small ribosomal subunit protein uS12A (Gene Name=RPS23A)