Structure of PDB 8tw8 Chain 2

Receptor sequence
>8tw82 (length=340) Species: 4932 (Saccharomyces cerevisiae) [Search protein sequence]
SKLAAEQSLAQQPWVEKYRPKNLDEVTAQDHAVTVLKKTLKSANLPHMLF
YGPPGTGKTSTILALTKELYGPDLMKSRILELNASDERGISIVREKVKNF
ARLTVSKPSKHDLENYPCPPYKIIILDEADSMTADAQSALRRTMETYSGV
TRFCLICNYVTRIIDPLASRCSKFRFKALDASNAIDRLRFISEQENVKCD
DGVLERILDISAGDLRRGITLLQSASKGAQYLGDGKNITSTQVEELAGVV
PHDILIEIVEKVKSGDFDEIKKYVNTFMKSGWSAASVVNQLHEYYITNDN
FDTNFKNQISWLLFTTDSRLNNGTNEHIQLLNLLVKISQL
3D structure
PDB8tw8 Cryo-EM reveals that Ctf18-RFC collaborates with PolE to load the PCNA clamp onto a leading strand DNA
Chain2
Resolution3.5 Å
3D
structure
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Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 AGS 2 V28 R32 P33 P67 G68 T69 G70 K71 T72 S73 N171 L228 R229 V15 R19 P20 P54 G55 T56 G57 K58 T59 S60 N158 L215 R216
BS02 MG 2 T72 D140 T59 D127
External links
PDB RCSB:8tw8, PDBe:8tw8, PDBj:8tw8
PDBsum8tw8
PubMed
UniProtP40348|RFC2_YEAST Replication factor C subunit 2 (Gene Name=RFC2)

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