Structure of PDB 8r6c Chain 2

Receptor sequence

>8r6c2 (length=64) Species: 679895 (Escherichia coli BW25113)

PKIKTVRGAAKRFKKTGKGGFKHKHANLRHILTKKATKRKRHLRPKAMVS
KGDLGLVIACLPYA

3D structure

• PDB: 8r6c Paenilamicins from the honey bee pathogen Paenibacillus larvae are context-specific translocation inhibitors of protein synthesis.
• Chain: 2
• Resolution: 2.2 Å

Interaction with ligand

Site #	Ligand	Ligand chain	Binding residues on receptor (original residue number in PDB)	Binding residues on receptor (residue number reindexed from 1)	Binding affinity
BS01	rna	2	P2 K3 I4 K5 T6 R8 K12 R13 T17 G18 K19 K23 H26 A27 N28 R30 H31 I32 L33 T34 K35 T38 K39 R40 K41 R42 H43 R45 K47 M49 S51 K52 G53 D54 Y64	P1 K2 I3 K4 T5 R7 K11 R12 T16 G17 K18 K22 H25 A26 N27 R29 H30 I31 L32 T33 K34 T37 K38 R39 K40 R41 H42 R44 K46 M48 S50 K51 G52 D53 Y63

Gene Ontology

Molecular Function

• GO:0003735 structural constituent of ribosome

Biological Process

• GO:0002181 cytoplasmic translation
• GO:0006412 translation

Cellular Component

• GO:0005737 cytoplasm
• GO:0005840 ribosome
• GO:0022625 cytosolic large ribosomal subunit
• GO:1990904 ribonucleoprotein complex

External links

• PDB: RCSB:8r6c, PDBe:8r6c, PDBj:8r6c
• PDBsum: 8r6c
• PubMed: 38826346
• UniProt: P0A7Q1|RL35_ECOLI Large ribosomal subunit protein bL35 (Gene Name=rpmI)