Structure of PDB 8fn6 Chain 2

Receptor sequence
>8fn62 (length=428) Species: 5691 (Trypanosoma brucei) [Search protein sequence]
DFSHITRNTVWGLWNEGNLFSLSVPELAFFLQEHCRVANVDPRAKKSALV
RQVEEILSAEQQASATVPQEDNPHAIVVTDYEEADEYGDWGAEPGFEDRR
ELDFMELSPRYDPLSPRAFQLLHSETATDVGIASIDPSKLPGQSKVKNAL
AAIHVAPNDANKMRFRMAFEWCLMNIWNMNMPGELNIGAGKALYYRSVAK
QNRNVMPLWTVQKHLYAQHPYAWFAIASESNVAAMESLAAALNMSIQQER
TTSYKVTIRRMAEFFDCELNGQLKCTMMNKPWDRFFVSHYIRSKMPDLRY
VVRARHPIKKRIADAYLEADILRSTRDSVQSVLSPELGDVVYCCERVVRK
WAKKTATGVTLQLVETKRTPLIITKAGDEGERLEYEWIVPLPQQAERIDI
AALTDELWEYGNKLAAALEEGMEELMVH
3D structure
PDB8fn6 Structural basis of gRNA stabilization and mRNA recognition in trypanosomal RNA editing.
Chain2
Resolution3.7 Å
3D
structure
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Enzymatic activity
Enzyme Commision number ?
Interaction with ligand
Site
#
Ligand Ligand
chain
Binding residues on receptor
(original residue number in PDB)
Binding residues on receptor
(residue number reindexed from 1)
Binding affinity
BS01 rna 2 L170 P172 H275 A278 W279 R340 L114 P116 H219 A222 W223 R284
BS02 ATP 2 K311 W338 R359 R402 R424 K431 K255 W282 R303 R346 R368 K375
Gene Ontology
Molecular Function
GO:0003723 RNA binding
GO:0005515 protein binding
Biological Process
GO:0043489 RNA stabilization

View graph for
Molecular Function

View graph for
Biological Process
External links
PDB RCSB:8fn6, PDBe:8fn6, PDBj:8fn6
PDBsum8fn6
PubMed37410820
UniProtB6SBL9

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