Structure of PDB 8cre Chain 2

Receptor sequence

>8cre2 (length=159) Species: 5476 (Candida albicans) [Search protein sequence]

GKSRGYRSGTRYAFQRDFKKHGAIPLSTYLKVYKVGDIVDIKANGSIQKG
MPHKYYHGKTGIVYNVTKSSVGVIINKVVGNRYIEKRVNLRVEHVKHSAC
RQEFLNRVKSNAAKKREAKANGETVYLKRQAAKPRGSRIISTEGNIPQTL
APVAYETFI

3D structure

PDB

8cre Drug-induced rotational movement of the ribosome is a key factor for read-through enhancement

Chain

Resolution

3.0 Å

3D
structure

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Interaction with ligand

Site #	Ligand	Ligand chain	Binding residues on receptor (original residue number in PDB)	Binding residues on receptor (residue number reindexed from 1)	Binding affinity
BS01	rna	2	G2 K3 S4 R5 G6 Y7 R8 S9 R12 Y13 A14 Q16 R17 F19 H22 G23 K35 D41 G46 S47 Q49 K50 G51 H54 K55 Y57 H58 G59 K60 T61 T68 K69 S70 S71 K78 V80 R83 K87 R88 N90 R92 A100 C101 R102 E104 F105 R108 V109 K116 K120 Y127 K129 R130	G1 K2 S3 R4 G5 Y6 R7 S8 R11 Y12 A13 Q15 R16 F18 H21 G22 K34 D40 G45 S46 Q48 K49 G50 H53 K54 Y56 H57 G58 K59 T60 T67 K68 S69 S70 K77 V79 R82 K86 R87 N89 R91 A99 C100 R101 E103 F104 R107 V108 K115 K119 Y126 K128 R129
BS02	rna	2	P26 S28	P25 S27

External links

PDB	RCSB:8cre, PDBe:8cre, PDBj:8cre
PDBsum	8cre
PubMed
UniProt	A0A8H6F1C8

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