Structure of PDB 6q8w Chain 2

Receptor sequence
>6q8w2 (length=178) Species: 300852 (Thermus thermophilus HB8) [Search protein sequence]
FFDDKQDFLEETFAKYPPEGRRAAIMPLLRRVQQEEGWIRPERIEEIARL
VGTTPTEVMGVASFYSYYQFVPTGKYHLQVCATLSCKLAGAEELWDYLTE
TLGIGPGEVTPDGLFSVQKVECLGSCHTAPVIQVNDEPYVECVTRARLEA
LLAGLRAGKRLEEIELPGKCGHHVHEVE
3D structure
PDB6q8w Key role of quinone in the mechanism of respiratory complex I.
Chain2
Resolution3.4 Å
3D
structure
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Enzymatic activity
Enzyme Commision number 7.1.1.-
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 FES 2 C83 C88 C124 L125 G126 S127 C128 C81 C86 C122 L123 G124 S125 C126
Gene Ontology
Molecular Function
GO:0003954 NADH dehydrogenase activity
GO:0016491 oxidoreductase activity
GO:0046872 metal ion binding
GO:0048038 quinone binding
GO:0051537 2 iron, 2 sulfur cluster binding
Cellular Component
GO:0005886 plasma membrane
GO:0045271 respiratory chain complex I

View graph for
Molecular Function
View graph for
Cellular Component
External links
PDB RCSB:6q8w, PDBe:6q8w, PDBj:6q8w
PDBsum6q8w
PubMed32811817
UniProtQ56221|NQO2_THET8 NADH-quinone oxidoreductase subunit 2 (Gene Name=nqo2)

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