Structure of PDB 5zwm Chain 2

Receptor sequence
>5zwm2 (length=211) Species: 559292 (Saccharomyces cerevisiae S288C) [Search protein sequence]
KPSLSQLKSQVPYPQIIEWYDCDARYPGLLASIKCTKNVIPVPSHWQSKK
EYLSGRSLLGKRPFELPDIIKKTNIEQMRSTLPALDLDYKKLHDVFFKIG
ANWKPDHLLCFGDVYYENRNLFEETNWKRMVDHKRPGRISQELRAIMNLP
EGQLPPWCMKMKDIGLPTGYPDLKIAGLNWDITNLKGDVYGKIIPRNYFG
ALISFETPEFE
3D structure
PDB5zwm Structures of the fully assembledSaccharomyces cerevisiaespliceosome before activation
Chain2
Resolution3.4 Å
3D
structure
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Enzymatic activity
Enzyme Commision number ?
Interaction with ligand
Site
#
Ligand Ligand
chain
Binding residues on receptor
(original residue number in PDB)
Binding residues on receptor
(residue number reindexed from 1)
Binding affinity
BS01 rna 2 W149 D153 Q177 W19 D23 Q47
Gene Ontology
Molecular Function
GO:0003674 molecular_function
GO:0003723 RNA binding
GO:0005515 protein binding
Biological Process
GO:0000245 spliceosomal complex assembly
GO:0000398 mRNA splicing, via spliceosome
GO:0006397 mRNA processing
GO:1903241 U2-type prespliceosome assembly
Cellular Component
GO:0005634 nucleus
GO:0005681 spliceosomal complex
GO:0005684 U2-type spliceosomal complex
GO:0005686 U2 snRNP
GO:0071004 U2-type prespliceosome
GO:0071011 precatalytic spliceosome
GO:0071013 catalytic step 2 spliceosome

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Molecular Function

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Biological Process

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Cellular Component
External links
PDB RCSB:5zwm, PDBe:5zwm, PDBj:5zwm
PDBsum5zwm
PubMed29794219
UniProtQ02554|CUS1_YEAST Cold sensitive U2 snRNA suppressor 1 (Gene Name=CUS1)

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