Structure of PDB 8vtv Chain 1s

Receptor sequence
>8vtv1s (length=83) Species: 300852 (Thermus thermophilus HB8) [Search protein sequence]
PRSLKKGVFVDDHLLEKVLELNAKGEKRLIKTWSRRSTIVPEMVGHTIAV
YNGKQHVPVYITENMVGHKLGEFAPTRTYRGHG
3D structure
PDB8vtv Macrolones target bacterial ribosomes and DNA gyrase and can evade resistance mechanisms.
Chain1s
Resolution2.55 Å
3D
structure
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Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 rna 1s P2 R3 S4 L5 K7 F10 H14 K18 W34 R36 R37 Y52 G54 K55 G72 E73 T77 R78 Y80 H83 P1 R2 S3 L4 K6 F9 H13 K17 W33 R35 R36 Y51 G53 K54 G71 E72 T76 R77 Y79 H82
External links
PDB RCSB:8vtv, PDBe:8vtv, PDBj:8vtv
PDBsum8vtv
PubMed39039256
UniProtQ5SHP2|RS19_THET8 Small ribosomal subunit protein uS19 (Gene Name=rpsS)

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