Structure of PDB 8uvs Chain 1s

Receptor sequence
>8uvs1s (length=83) Species: 300852 (Thermus thermophilus HB8) [Search protein sequence]
PRSLKKGVFVDDHLLEKVLELNAKGEKRLIKTWSRRSTIVPEMVGHTIAV
YNGKQHVPVYITENMVGHKLGEFAPTRTYRGHG
3D structure
PDB8uvs Development of 2nd generation aminomethyl spectinomycins that overcome native efflux in Mycobacterium abscessus.
Chain1s
Resolution2.75 Å
3D
structure
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Interaction with ligand
Site
#
Ligand Ligand
chain
Binding residues on receptor
(original residue number in PDB)
Binding residues on receptor
(residue number reindexed from 1)
Binding affinity
BS01 rna 1s P2 R3 S4 L5 K6 K7 F10 H14 K18 W34 R36 R37 Y52 N53 G54 K55 K70 G72 T77 R78 T79 Y80 H83 P1 R2 S3 L4 K5 K6 F9 H13 K17 W33 R35 R36 Y51 N52 G53 K54 K69 G71 T76 R77 T78 Y79 H82
External links
PDB RCSB:8uvs, PDBe:8uvs, PDBj:8uvs
PDBsum8uvs
PubMed38165935
UniProtQ5SHP2|RS19_THET8 Small ribosomal subunit protein uS19 (Gene Name=rpsS)

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