Structure of PDB 8uvs Chain 1r

Receptor sequence
>8uvs1r (length=68) Species: 300852 (Thermus thermophilus HB8) [Search protein sequence]
AKVKATLGEFDLRDYRNVEVLKRFLSETGKILPRRRTGLSAKEQRILAKT
IKRARILGLLPFTEKLVR
3D structure
PDB8uvs Development of 2nd generation aminomethyl spectinomycins that overcome native efflux in Mycobacterium abscessus.
Chain1r
Resolution2.75 Å
3D
structure
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Interaction with ligand
Site
#
Ligand Ligand
chain
Binding residues on receptor
(original residue number in PDB)
Binding residues on receptor
(residue number reindexed from 1)
Binding affinity
BS01 rna 1r K49 I50 R53 A60 K61 Q63 R64 K68 K71 R72 R74 I75 F81 K30 I31 R34 A41 K42 Q44 R45 K49 K52 R53 R55 I56 F62
External links
PDB RCSB:8uvs, PDBe:8uvs, PDBj:8uvs
PDBsum8uvs
PubMed38165935
UniProtQ5SLQ0|RS18_THET8 Small ribosomal subunit protein bS18 (Gene Name=rpsR)

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