Structure of PDB 8vtw Chain 1j

Receptor sequence
>8vtw1j (length=97) Species: 300852 (Thermus thermophilus HB8) [Search protein sequence]
IRIKLRGFDHKTLDASAQKIVEAARRSGAQVSGPIPLPTRVRRFTVIRGP
FKHKDSREHFELRTHNRLVDIINPNRKTIEQLMTLDLPTGVEIEIKT
3D structure
PDB8vtw Macrolones target bacterial ribosomes and DNA gyrase and can evade resistance mechanisms.
Chain1j
Resolution2.35 Å
3D
structure
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Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 rna 1j R5 K7 H13 D17 S35 G36 P37 I38 P39 L40 P41 R43 V44 R45 T48 R51 G52 P53 F54 K55 H56 K57 S59 R60 H62 H68 L71 R2 K4 H10 D14 S32 G33 P34 I35 P36 L37 P38 R40 V41 R42 T45 R48 G49 P50 F51 K52 H53 K54 S56 R57 H59 H65 L68
External links
PDB RCSB:8vtw, PDBe:8vtw, PDBj:8vtw
PDBsum8vtw
PubMed39039256
UniProtQ5SHN7|RS10_THET8 Small ribosomal subunit protein uS10 (Gene Name=rpsJ)

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