Structure of PDB 8vtw Chain 1g

Receptor sequence
>8vtw1g (length=155) Species: 300852 (Thermus thermophilus HB8) [Search protein sequence]
ARRRRAEVRQLQPDLVYGDVLVTAFINKIMRDGKKNLAARIFYDACKIIQ
EKTGQEPLKVFKQAVENVKPRMEVRSRRVGGANYQVPMEVSPRRQQSLAL
RWLVQAANQRPERRAAVRIAHELMDAAEGKGGAVKKKEDVERMAEANRAY
AHYRW
3D structure
PDB8vtw Macrolones target bacterial ribosomes and DNA gyrase and can evade resistance mechanisms.
Chain1g
Resolution2.35 Å
3D
structure
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Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 rna 1g A2 R3 R4 R6 A7 R10 N28 K29 I30 M31 R32 D33 G34 K35 K36 N37 L38 R41 I42 G82 R94 R95 S98 R102 N109 R114 R115 A116 R119 A1 R2 R3 R5 A6 R9 N27 K28 I29 M30 R31 D32 G33 K34 K35 N36 L37 R40 I41 G81 R93 R94 S97 R101 N108 R113 R114 A115 R118
External links
PDB RCSB:8vtw, PDBe:8vtw, PDBj:8vtw
PDBsum8vtw
PubMed39039256
UniProtP17291|RS7_THET8 Small ribosomal subunit protein uS7 (Gene Name=rpsG)

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