Structure of PDB 8uvs Chain 1c

Receptor sequence
>8uvs1c (length=206) Species: 300852 (Thermus thermophilus HB8) [Search protein sequence]
GNKIHPIGFRLGITRDWESRWYAGKKQYRHLLLEDQRIRGLLEKELYSAG
LARVDIERAADNVAVTVHVAKPGVVIGRGGERIRVLREELAKLTGKNVAL
NVQEVQNPNLSAPLVAQRVAEQIERRFAVRRAIKQAVQRVMESGAKGAKV
IVSGRIGGAEQARTEWAAQGRVPLHTLRANIDYGFALARTTYGVLGVKAY
IFLGEV
3D structure
PDB8uvs Development of 2nd generation aminomethyl spectinomycins that overcome native efflux in Mycobacterium abscessus.
Chain1c
Resolution2.75 Å
3D
structure
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Interaction with ligand
Site
#
Ligand Ligand
chain
Binding residues on receptor
(original residue number in PDB)
Binding residues on receptor
(residue number reindexed from 1)
Binding affinity
BS01 rna 1c G2 N3 K4 I5 F10 I14 K26 R127 S154 R156 E161 Q162 A163 R172 V173 L175 H176 T177 L178 R179 T192 Y193 G194 V195 G197 K199 G1 N2 K3 I4 F9 I13 K25 R126 S153 R155 E160 Q161 A162 R171 V172 L174 H175 T176 L177 R178 T191 Y192 G193 V194 G196 K198
External links
PDB RCSB:8uvs, PDBe:8uvs, PDBj:8uvs
PDBsum8uvs
PubMed38165935
UniProtP80372|RS3_THET8 Small ribosomal subunit protein uS3 (Gene Name=rpsC)

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