Structure of PDB 8vtv Chain 1b

Receptor sequence
>8vtv1b (length=231) Species: 300852 (Thermus thermophilus HB8) [Search protein sequence]
VKELLEAGVHFGHERKRWNPKFARYIYAERNGIHIIDLQKTMEELERTFR
FIEDLAMRGGTILFVGTKKQAQDIVRMEAERAGMPYVNQRWLGGMLTNFK
TISQRVHRLEELEALFASPEIEERPKKEQVRLKHELERLQKYLSGFRLLK
RLPDAIFVVDPTKEAIAVREARKLFIPVIALADTDSDPDLVDYIIPGNDD
AIRSIQLILSRAVDLIIQARGGVVEPSPSYA
3D structure
PDB8vtv Macrolones target bacterial ribosomes and DNA gyrase and can evade resistance mechanisms.
Chain1b
Resolution2.55 Å
3D
structure
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Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 rna 1b W24 P26 R96 G99 G100 T103 N104 R111 I172 E176 K179 W18 P20 R90 G93 G94 T97 N98 R105 I166 E170 K173
External links
PDB RCSB:8vtv, PDBe:8vtv, PDBj:8vtv
PDBsum8vtv
PubMed39039256
UniProtP80371|RS2_THET8 Small ribosomal subunit protein uS2 (Gene Name=rpsB)

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