Structure of PDB 5hcp Chain 1Z

Receptor sequence
>5hcp1Z (length=186) Species: 300852 (Thermus thermophilus HB8) [Search protein sequence]
MEYRLKAYYREGEKPSALRRAGKLPGVMYNRHLNRKVYVDLVEFDKVFRQ
ASIHHVIVLELPDGQSLPTLVRQVNLDKRRRRPEHVDFFVLSDEPVEMYV
PLRFVGTPAGVRAGGVLQEIHRDILVKVSPRNIPEFIEVDVSGLEIGDSL
HASDLKLPPGVELAVSPEETIAAVVPPEDVEKLAEE
3D structure
PDB5hcp Structures of proline-rich peptides bound to the ribosome reveal a common mechanism of protein synthesis inhibition.
Chain1Z
Resolution2.894 Å
3D
structure
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Enzymatic activity
Enzyme Commision number ?
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 rna 1Z I146 S149 H151 E169 V175 P176 I146 S149 H151 E169 V175 P176
BS02 rna 1Z R10 P15 R19 Y29 N30 R31 N34 R72 Q73 R79 E84 H85 R10 P15 R19 Y29 N30 R31 N34 R72 Q73 R79 E84 H85
Gene Ontology
Molecular Function
GO:0003723 RNA binding
GO:0003735 structural constituent of ribosome
GO:0008097 5S rRNA binding
GO:0019843 rRNA binding
Biological Process
GO:0006412 translation
Cellular Component
GO:0005840 ribosome
GO:0022625 cytosolic large ribosomal subunit
GO:1990904 ribonucleoprotein complex

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Molecular Function
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Cellular Component
External links
PDB RCSB:5hcp, PDBe:5hcp, PDBj:5hcp
PDBsum5hcp
PubMed26809677
UniProtQ5SHZ1|RL25_THET8 Large ribosomal subunit protein bL25 (Gene Name=rplY)

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