Structure of PDB 8vtv Chain 1O

Receptor sequence
>8vtv1O (length=122) Species: 300852 (Thermus thermophilus HB8) [Search protein sequence]
MIQPQTYLEVADNTGARKIMCIRVLKGSNAKYATVGDVIVASVKEAIPRG
AVKEGDVVKAVVVRTKKEIKRPDGSAIRFDDNAAVIINNQLEPRGTRVFG
PVARELREKGFMKIVSLAPEVL
3D structure
PDB8vtv Macrolones target bacterial ribosomes and DNA gyrase and can evade resistance mechanisms.
Chain1O
Resolution2.55 Å
3D
structure
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Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 rna 1O M1 Q3 Q5 T6 Y7 I22 R23 L25 S28 N29 K31 Y32 S42 K44 K66 K67 E68 K70 M1 Q3 Q5 T6 Y7 I22 R23 L25 S28 N29 K31 Y32 S42 K44 K66 K67 E68 K70
BS02 rna 1O N13 P48 R49 T96 R97 R107 N13 P48 R49 T96 R97 R107
BS03 MG 1O D12 I86 R94 G95 D12 I86 R94 G95
External links
PDB RCSB:8vtv, PDBe:8vtv, PDBj:8vtv
PDBsum8vtv
PubMed39039256
UniProtQ5SHP8|RL14_THET8 Large ribosomal subunit protein uL14 (Gene Name=rplN)

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