Structure of PDB 8uvs Chain 1O

Receptor sequence
>8uvs1O (length=122) Species: 300852 (Thermus thermophilus HB8) [Search protein sequence]
MIQPQTYLEVADNTGARKIMCIRVLKGSNAKYATVGDVIVASVKEAIPRG
AVKEGDVVKAVVVRTKKEIKRPDGSAIRFDDNAAVIINNQLEPRGTRVFG
PVARELREKGFMKIVSLAPEVL
3D structure
PDB8uvs Development of 2nd generation aminomethyl spectinomycins that overcome native efflux in Mycobacterium abscessus.
Chain1O
Resolution2.75 Å
3D
structure
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Interaction with ligand
Site
#
Ligand Ligand
chain
Binding residues on receptor
(original residue number in PDB)
Binding residues on receptor
(residue number reindexed from 1)
Binding affinity
BS01 rna 1O M1 Q5 T6 Y7 I22 R23 L25 K26 S28 N29 K31 Y32 S42 K44 K66 K67 E68 K70 M1 Q5 T6 Y7 I22 R23 L25 K26 S28 N29 K31 Y32 S42 K44 K66 K67 E68 K70
BS02 rna 1O N13 P48 R49 T96 R97 R107 N13 P48 R49 T96 R97 R107
BS03 MG 1O R49 G50 R49 G50
BS04 MG 1O D12 G95 D12 G95
External links
PDB RCSB:8uvs, PDBe:8uvs, PDBj:8uvs
PDBsum8uvs
PubMed38165935
UniProtQ5SHP8|RL14_THET8 Large ribosomal subunit protein uL14 (Gene Name=rplN)

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