Structure of PDB 7rqc Chain 1O

Receptor sequence
>7rqc1O (length=122) Species: 300852 (Thermus thermophilus HB8) [Search protein sequence]
MIQPQTYLEVADNTGARKIMCIRVLKGSNAKYATVGDVIVASVKEAIPRG
AVKEGDVVKAVVVRTKKEIKRPDGSAIRFDDNAAVIINNQLEPRGTRVFG
PVARELREKGFMKIVSLAPEVL
3D structure
PDB7rqc Structural basis for the context-specific action of the classic peptidyl transferase inhibitor chloramphenicol.
Chain1O
Resolution2.5 Å
3D
structure
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Enzymatic activity
Enzyme Commision number ?
Interaction with ligand
Site
#
Ligand Ligand
chain
Binding residues on receptor
(original residue number in PDB)
Binding residues on receptor
(residue number reindexed from 1)
Binding affinity
BS01 rna 1O M1 Q3 Q5 T6 Y7 I22 R23 G27 S28 N29 A30 K31 Y32 S42 K44 K66 K67 E68 K70 N82 M1 Q3 Q5 T6 Y7 I22 R23 G27 S28 N29 A30 K31 Y32 S42 K44 K66 K67 E68 K70 N82
BS02 rna 1O N13 P48 R49 T96 R97 F99 R107 N13 P48 R49 T96 R97 F99 R107
BS03 MG 1O A11 R64 F99 A11 R64 F99
Gene Ontology
Molecular Function
GO:0003735 structural constituent of ribosome
GO:0019843 rRNA binding
GO:0070180 large ribosomal subunit rRNA binding
Biological Process
GO:0006412 translation
Cellular Component
GO:0005840 ribosome
GO:0015934 large ribosomal subunit
GO:0022625 cytosolic large ribosomal subunit
GO:1990904 ribonucleoprotein complex

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Molecular Function

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Biological Process

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Cellular Component
External links
PDB RCSB:7rqc, PDBe:7rqc, PDBj:7rqc
PDBsum7rqc
PubMed35165455
UniProtQ5SHP8|RL14_THET8 Large ribosomal subunit protein uL14 (Gene Name=rplN)

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