Structure of PDB 8uep Chain 1I

Receptor sequence
>8uep1I (length=176) Species: 9823 (Sus scrofa) [Search protein sequence]
TYKFVNMREPSMDMKSVTDRAAQTLLWTELVRGLGMTLSYLFREPATINY
PFEKGPLSPRFRGEHALRRYPSGEERCIACKLCEAVCPAQAITIEAEPRA
DGSRRTTRYDIDMTKCIYCGFCQEACPVDAIVEGPNFEFSTETHEELLYN
KEKLLNNGDKWEAEIAANIQADYLYR
3D structure
PDB8uep High-resolution in situ structures of mammalian respiratory supercomplexes.
Chain1I
Resolution3.4 Å
3D
structure
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Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 SF4 1I H65 C87 I92 C116 I117 Y118 C119 G120 C122 E133 H65 C87 I92 C116 I117 Y118 C119 G120 C122 E133
BS02 SF4 1I C77 I78 A79 C80 K81 L82 C83 Y109 C126 A130 I131 C77 I78 A79 C80 K81 L82 C83 Y109 C126 A130 I131
Gene Ontology
Molecular Function
GO:0003954 NADH dehydrogenase activity
GO:0008137 NADH dehydrogenase (ubiquinone) activity
GO:0051539 4 iron, 4 sulfur cluster binding
Biological Process
GO:0006120 mitochondrial electron transport, NADH to ubiquinone
GO:0032981 mitochondrial respiratory chain complex I assembly
GO:1902600 proton transmembrane transport
Cellular Component
GO:0005739 mitochondrion
GO:0005743 mitochondrial inner membrane
GO:0045271 respiratory chain complex I

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External links
PDB RCSB:8uep, PDBe:8uep, PDBj:8uep
PDBsum8uep
PubMed38811722
UniProtA0A286ZUN9

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