Structure of PDB 5kcs Chain 1H

Receptor sequence
>5kcs1H (length=176) Species: 83333 (Escherichia coli K-12) [Search protein sequence]
SRVAKAPVVVPAGVDVKINGQVITIKGKNGELTRTLNDAVEVKHADNTLT
FGPRDGYADGWAQAGTARALLNSMVIGVTEGFTKKLQLVGVGYRAAVKGN
VINLSLGFSHPVDHQLPAGITAECPTQTEIVLKGADKQVIGQVAADLRAY
RRPEPYKGKGVRYADEVVRTKEAKKK
3D structure
PDB5kcs Structures of the orthosomycin antibiotics avilamycin and evernimicin in complex with the bacterial 70S ribosome.
Chain1H
Resolution3.9 Å
3D
structure
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Enzymatic activity
Enzyme Commision number ?
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 rna 1H S1 R2 V3 R34 N37 A62 Q63 G65 T66 A69 L70 F108 S109 H110 K137 Q138 G141 Q142 R151 R152 Y156 K157 K171 K174 S1 R2 V3 R34 N37 A62 Q63 G65 T66 A69 L70 F108 S109 H110 K137 Q138 G141 Q142 R151 R152 Y156 K157 K171 K174
Gene Ontology
Molecular Function
GO:0003735 structural constituent of ribosome
GO:0019843 rRNA binding
GO:0070180 large ribosomal subunit rRNA binding
Biological Process
GO:0000027 ribosomal large subunit assembly
GO:0002181 cytoplasmic translation
GO:0006412 translation
GO:0046677 response to antibiotic
Cellular Component
GO:0005737 cytoplasm
GO:0005829 cytosol
GO:0005840 ribosome
GO:0022625 cytosolic large ribosomal subunit
GO:1990904 ribonucleoprotein complex

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Molecular Function
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Biological Process
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Cellular Component
External links
PDB RCSB:5kcs, PDBe:5kcs, PDBj:5kcs
PDBsum5kcs
PubMed27330110
UniProtP0AG55|RL6_ECOLI Large ribosomal subunit protein uL6 (Gene Name=rplF)

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