Structure of PDB 6o2t Chain 1F

Receptor sequence
>6o2t1F (length=437) Species: 9823 (Sus scrofa) [Search protein sequence]
MRECISIHVGQAGVQIGNACWELYCLEHGIQPDGQMPSDGGDDSFNTFFS
ETGAGKHVPRAVFVDLEPTVIDEVRTGTYRQLFHPEQLITGKEDAANNYA
RGHYTIGKEIIDLVLDRIRKLADQCTGLQGFLVFHSFGGGTGSGFTSLLM
ERLSVDYGKKSKLEFSIYPAPQVSTAVVEPYNSILTTHTTLEHSDCAFMV
DNEAIYDICRRNLDIERPTYTNLNRLISQIVSSITASLRFDGALNVDLTE
FQTNLVPYPRIHFPLATYAPVISAEKAYHEQLSVAEITNACFEPANQMVK
CDPRHGKYMACCLLYRGDVVPKDVNAAIATIKTKRSIQFVDWCPTGFKVG
INYQPPTVVPGGDLAKVQRAVCMLSNTTAIAEAWARLDHKFDLMYAKRAF
VHWYVGEGMEEGEFSEAREDMAALEKDYEEVGVDSVE
3D structure
PDB6o2t Effects of alpha-tubulin acetylation on microtubule structure and stability.
Chain1F
Resolution4.1 Å
3D
structure
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Enzymatic activity
Enzyme Commision number 3.6.5.-
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 GTP 1F G10 Q11 A12 Q15 A99 A100 N101 S140 G143 G144 T145 G146 T179 N206 Y224 N228 G10 Q11 A12 Q15 A95 A96 N97 S136 G139 G140 T141 G142 T175 N202 Y220 N224
Gene Ontology
Molecular Function
GO:0003924 GTPase activity
GO:0005200 structural constituent of cytoskeleton
GO:0005525 GTP binding
GO:0016787 hydrolase activity
GO:0046872 metal ion binding
Biological Process
GO:0000226 microtubule cytoskeleton organization
GO:0000278 mitotic cell cycle
GO:0007017 microtubule-based process
Cellular Component
GO:0005737 cytoplasm
GO:0005856 cytoskeleton
GO:0005874 microtubule
GO:0015630 microtubule cytoskeleton

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Molecular Function
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Biological Process
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Cellular Component
External links
PDB RCSB:6o2t, PDBe:6o2t, PDBj:6o2t
PDBsum6o2t
PubMed31072936
UniProtQ2XVP4|TBA1B_PIG Tubulin alpha-1B chain (Gene Name=TUBA1B)

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