Structure of PDB 8uex Chain 1E

Receptor sequence
>8uex1E (length=214) Species: 9823 (Sus scrofa) [Search protein sequence]
GALFVHRDTPENNPDTPFDFTPENYKRIEAIVKNYPEGHKAAAVLPVLDL
AQRQNGWLPISAMNKVAEILQVPPMRVYEVATFYTMYNRKPVGKYHIQVC
TTTPCMLRNSDSILEAIQKKLGIKVGETTPDKLFTLIEVECLGACVNAPM
VQINDNYYEDLTPKDIEEIIDELKAGKIPKPGPRSGRFSCEPAGGLTSLT
EPPKGPGFGVQAGL
3D structure
PDB8uex High-resolution in situ structures of mammalian respiratory supercomplexes.
Chain1E
Resolution3.9 Å
3D
structure
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Interaction with ligand
Site
#
Ligand Ligand
chain
Binding residues on receptor
(original residue number in PDB)
Binding residues on receptor
(residue number reindexed from 1)
Binding affinity
BS01 FES 1E C103 T105 C108 C144 L145 G146 A147 C148 M153 C100 T102 C105 C141 L142 G143 A144 C145 M150
Gene Ontology
Molecular Function
GO:0008137 NADH dehydrogenase (ubiquinone) activity
GO:0046872 metal ion binding
GO:0051537 2 iron, 2 sulfur cluster binding
Biological Process
GO:0006120 mitochondrial electron transport, NADH to ubiquinone
GO:0007399 nervous system development
GO:0048738 cardiac muscle tissue development
GO:1902600 proton transmembrane transport
Cellular Component
GO:0005739 mitochondrion
GO:0005743 mitochondrial inner membrane
GO:0045271 respiratory chain complex I

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Molecular Function

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Cellular Component
External links
PDB RCSB:8uex, PDBe:8uex, PDBj:8uex
PDBsum8uex
PubMed38811722
UniProtA0A4X1VRV3

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