Structure of PDB 8vtv Chain 19

Receptor sequence
>8vtv19 (length=37) Species: 300852 (Thermus thermophilus HB8) [Search protein sequence]
MKVRASVKRICDKCKVIRRHGRVYVICENPKHKQRQG
3D structure
PDB8vtv Macrolones target bacterial ribosomes and DNA gyrase and can evade resistance mechanisms.
Chain19
Resolution2.55 Å
3D
structure
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Interaction with ligand
Site
#
Ligand Ligand
chain
Binding residues on receptor
(original residue number in PDB)
Binding residues on receptor
(residue number reindexed from 1)
Binding affinity
BS01 rna 19 M1 K2 R4 A5 S6 V7 K15 R19 H20 R22 K31 K33 R35 Q36 G37 M1 K2 R4 A5 S6 V7 K15 R19 H20 R22 K31 K33 R35 Q36 G37
BS02 ZN 19 C11 C14 C27 H32 C11 C14 C27 H32
External links
PDB RCSB:8vtv, PDBe:8vtv, PDBj:8vtv
PDBsum8vtv
PubMed39039256
UniProtQ5SHR2|RL36_THET8 Large ribosomal subunit protein bL36 (Gene Name=rpmJ)

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