Structure of PDB 8vtw Chain 13

Receptor sequence
>8vtw13 (length=59) Species: 300852 (Thermus thermophilus HB8) [Search protein sequence]
PRLKVKLVKSPIGYPKDQKAALKALGLRRLQQERVLEDTPAIRGNVEKVA
HLVRVEVVE
3D structure
PDB8vtw Macrolones target bacterial ribosomes and DNA gyrase and can evade resistance mechanisms.
Chain13
Resolution2.35 Å
3D
structure
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Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 rna 13 K10 S11 I13 G14 Y15 P16 K17 D18 K20 A21 A22 K24 A25 R29 R30 L31 Q32 P41 A42 G45 N46 K49 K9 S10 I12 G13 Y14 P15 K16 D17 K19 A20 A21 K23 A24 R28 R29 L30 Q31 P40 A41 G44 N45 K48
BS02 rna 13 Y15 Q19 H52 Y14 Q18 H51
BS03 MG 13 K10 S11 K9 S10
BS04 MG 13 P16 D18 Q19 P15 D17 Q18
External links
PDB RCSB:8vtw, PDBe:8vtw, PDBj:8vtw
PDBsum8vtw
PubMed39039256
UniProtQ5SHQ6|RL30_THET8 Large ribosomal subunit protein uL30 (Gene Name=rpmD)

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